Ceftibuten is a third-generation cephalosporin antibiotic used for treating various bacterial infections. Here’s a comprehensive overview:
Description
Ceftibuten is effective against a broad spectrum of Gram-positive and Gram-negative bacteria. It is often used to treat infections of the respiratory tract and urinary tract.
Brand Names
- Cedax (brand name for ceftibuten)
- Ceftibuten (generic)
Available Forms & Strengths
- Oral Capsule: 400 mg
- Oral Suspension: 90 mg/5 mL
Uses
- Infections: Treats infections such as:
- Acute bacterial sinusitis
- Pharyngitis/tonsillitis
- Chronic bronchitis
- Uncomplicated urinary tract infections
Side Effects
Common side effects may include:
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Rash
Serious side effects can include:
- Allergic reactions (e.g., anaphylaxis)
- Severe gastrointestinal symptoms
- Liver enzyme abnormalities
Dose
- Typical Adult Dose: 400 mg orally once daily or divided into two doses, depending on the severity and type of infection.
- Children Dose: Based on weight and specific infection, typically administered as an oral suspension.
Contraindications
- Allergy: Known hypersensitivity to cephalosporins or penicillins.
- Renal Impairment: Caution and possible dose adjustment required in patients with renal dysfunction.
Drug Interactions
- Anticoagulants: May increase the risk of bleeding when used with anticoagulants like warfarin.
- Probenecid: Can increase ceftibuten levels in the blood.
- Other Antibiotics: Interaction with other antibiotics may impact effectiveness or side effects.
Warnings
- Renal Function: Monitor renal function, particularly in patients with preexisting conditions.
- Superinfection: Prolonged use can lead to superinfection or growth of non-susceptible organisms.
Doctor Advised
Follow your healthcare provider’s specific instructions for dosage and duration. Inform your doctor of any allergies, existing conditions, or if you experience any significant side effects.
