Sparfloxacin is a fluoroquinolone antibiotic used to treat various bacterial infections. Here’s an overview:
Description
Sparfloxacin is a broad-spectrum antibiotic effective against Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, which are crucial for bacterial DNA replication and repair.
Brand Names
- Zagam
- Sparflo
- Sparflox
- Sparflozin
- Sparlix
Available Forms & Strengths
- Tablets: Commonly available in 200 mg and 400 mg strengths.
Uses
- Respiratory Tract Infections (e.g., pneumonia, bronchitis)
- Urinary Tract Infections (UTIs)
- Skin and Soft Tissue Infections
- Sinusitis
- Prostatitis
- Gastrointestinal Infections (e.g., enteritis)
Side Effects
- Nausea
- Diarrhea
- Headache
- Dizziness
- Rash
- Insomnia
Dose
- Typically: 400 mg once daily, depending on the infection and physician’s instructions. The duration of treatment may vary based on the type and severity of the infection.
Contraindications
- Allergy to Sparfloxacin or other fluoroquinolones.
- Pregnancy: Use only if the benefits outweigh the risks.
- Children: Generally not recommended for children under 18 years.
- Severe Liver Impairment: Caution is advised.
Warnings
- Tendon Damage: Risk of tendonitis or tendon rupture, particularly in older adults and those taking corticosteroids.
- QT Prolongation: Can cause prolongation of the QT interval, leading to potential arrhythmias.
- Neurological Effects: Risk of seizures, tremors, or hallucinations.
- Photosensitivity: Increased sensitivity to sunlight, leading to a higher risk of sunburn.
- Drug Interactions: Can interact with medications like anticoagulants, antidiabetic agents, and others.
Consult a healthcare provider for personalized advice and treatment recommendations.
